Related Writings


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Links to rtf files marked with a pound <#>.


Articles of Interest

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Hundreds of scientific papers have been written on sickle cell and nutrition. In this section, we include both citations and complete articles on sickle cell anemia and related topics that we have found to be of special interest. For those interested in understanding the basis for the nutritional approach to sickle cell disease, the first two articles are particularly valuable.

Links to pdf files are marked with an asterisk <*>.

*Anti-sickling effect of dietary thyocyanate in prophylactic control of sickle cell anemia
Agbai, O
J Natl Med Assoc 1986 Nov;78(11):1053-6

*Sickle cell anemia and dietary precursors of cyanate
Houston RG
Am J Clin Nutr 1973 Nov;26(11):1261-4

Oral glutamine supplementation decreases resting energy expenditure in children and adolescents with sickle cell anemia.
Williams R, Olivi S, Li CS, Storm M, Cremer L, Mackert P, Wang W.
J Pediatr Hematol Oncol. 2004 Oct;26(10):619-25.


Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?
Morris CR, Morris SM Jr, Hagar W, Van Warmerdam J, Claster S, Kepka-Lenhart D, Machado L, Kuypers FA, Vichinsky EP.
Am J Respir Crit Care Med. 2003 Jul 1;168(1):63-9. Epub 2003 Mar 05.

Oral citrulline as arginine precursor may be beneficial in sickle cell disease: early phase two results.
Waugh WH, Daeschner CW 3rd, Files BA, McConnell ME, Strandjord SE.
J Natl Med Assoc. 2001 Oct;93(10):363-71.


In Vitro Effects of Aged Garlic Extract and Other Nutritional Supplements on Sickle Erythrocytes
Ohnishi ST, Ohnishi T.
J Nutr. 2001 Mar;131(3s):1085S-92S.


Body composition in children with sickle cell disease.
Barden EM, Kawchak DA, Ohene-Frempong K, Stallings VA, Zemel BS.
Am J Hematol. 2002 Apr;69(4):239-46.


Optimization of folic acid, vitamin B(12), and vitamin B(6) supplements in pediatric patients with sickle cell disease.
van der Dijs FP, Fokkema MR, Dijck-Brouwer DA, Niessink B, van der Wal TI, Schnog JJ, Duits AJ, Muskiet FD, Muskiet FA.
Am J Hematol. 2002 Apr;69(4):239-46.


Effect of zinc supplementation on growth and body composition in children with sickle cell disease.
Zemel BS, Kawchak DA, Fung EB, Ohene-Frempong K, Stallings VA.
Biochem Med Metab Biol. 1988 Feb;39(1):64-8.


Carbamylation of hemoglobin in vivo with chronic sublethal dietary cyanide: implications for hemoglobin S.
Jackson LC, Oseguera M, Medrano S, Kim YL.
Biochem Med Metab Biol. 1988 Feb;39(1):64-8.


Interaction of Antioxidants and Their Implication in Genetic Anemia
Chan AC, Chow CK, Chiu D.
Proc Soc Exp Biol Med. 1999 Dec;222(3):274-82.


High-dose vitamin C: a risk for persons with high iron stores?
Gerster H.
Int J Vitam Nutr Res. 1999 Mar;69(2):67-82.
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A decrease in irreversibly sickled erythrocytes in sickle cell anemia patients given vitamin E.
Natta CL, Machlin LJ, Brin M.
Am J Clin Nutr. 1980 May;33(5):968-71.


Zinc deficiency in patients with sickle cell disease
Prasad AS.
Am J Clin Nutr. 2002 Feb;75(2):181-2.